Monthly Archives: July 2007

Acomplia (rimonabant) and depression

The European Medicines Agency (EMEA) is recommending that rimonabant (indication: obesity) should not be used in those with major depression or those taking anti-depressants because of a risk of psychiatric side effects. Advice for patients taking rimonabant: If you are … Continue reading

Posted in EMEA, MHRA | Comments Off

Oseltamivir (Tamiflu) and causality

The Japan Institute of Pharmacovigilance has written to the BMJ concerning a editorial concerning oseltamivir. The letter states the following: On 16 June 2007 the Japanese Ministry of Health Labour and Welfare announced that by 31 May 2007 it had … Continue reading

Posted in ADRs, Spontaneous reporting | Comments Off

HRT and cardiovascular risk

The BMJ has published the WISDOM Trial of HRT in postmenopausal women aged 50 to 69 years-of-age (mean age 62.8 SD 4.8). Key points: Combined hormone therapy (n=2196) was compared with placebo (n=2189): significant increase in the number of major … Continue reading

Posted in ADRs, Patient Safety | Comments Off